Mission

Acytronix revolutionizes the purification of extracellular vesicles (EVs) with a mission to advance diagnostics and therapeutics. EVs are nano-sized vesicles secreted by cells in the body. They are bioactive, reflect the characteristics of their tissue of origin, and are distributed in bodily fluids.

Recognized as next-generation biomarkers and therapeutic agents, EVs hold tremendous potential. However, the need to isolate them from complex native matrices has limited their biomedical applications.

Acytronix, an ETH spin-off based in Schlieren, is led by CEO Dr. Vadim Krivitsky and CTO Dr. Adva Krivitsky. The company has developed a portable, easy-to-use device for isolating EVs directly from raw physiological fluids. This patent-protected device offers significant advantages over conventional EV isolation methods, enabling high-throughput separation of EV sub-populations based on surface marker expression—advancing EV-based liquid biopsy. Additionally, it uniquely allows EVs to be loaded with therapeutics on a single platform, opening new avenues for drug delivery applications.

The Problem

The separation of EVs from raw physiological fluids is a challenging task that often requires sample pretreatment and multiple steps, specialized laboratory equipment, and skilled operators. It may result in insufficient yield, low purity, and compromised integrity.

The Solution

At Acytronix, we have developed a portable device for the separation of EVs directly from physiological fluids.

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