Mission

Acytronix revolutionizes the purification of extracellular vesicles with a mission to advance diagnostics and therapeutics.
Extracellular vesicles (EVs) are nano-sized vesicles secreted by cells in our body. They are bioactive, represent the original tissue, and are distributed in bodily fluids.

They are recognized as next-generation biomarkers and therapeutic agents. However, the need to initially isolate them from the complex native matrix limits their biomedical application.

Acytronix is an ETH spin-off based in Schlieren. The management team includes CTO Dr.
Vadim Krivitsky and CEO Dr. Adva Krivitsky, with Prof. Jean-Christophe Leroux as the
scientific advisor. They have developed a portable, easy-to-use device for the isolation of
EVs from raw physiological fluids. This patent-protected device represents significant
progress compared to conventional methods for EVs isolation, as it enables high-throughput
isolation of EVs sub-populations according to surface marker expression, designed to
advance EV-based liquid biopsy. Moreover, it uniquely offers the option to load the EVs with
therapeutics on a single platform for drug delivery applications.

The Problem

The separation of EVs from raw physiological fluids is a challenging task that often requires sample pretreatment and multiple steps, specialized laboratory equipment, and skilled operators. It may result in insufficient yield, low purity, and compromised integrity.

The Solution

At Acytronix, we have developed a portable device for the separation of EVs directly from physiological fluids.

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